Dublin, Nov 04, 2009 (M2 PRESSWIRE via COMTEX News Network) --

Research and Markets (http://www.researchandmarkets.com/research/6cb3a2/annals_of_the_new) has announced the addition of John Wiley and Sons Ltd's new report "Annals of the New York Academy of Sciences, Immunology of Diabetes V" to their offering.

This volume an overview of current research in the field of immunology as it relates to diabetes. Topics covered include: autoantibody markers for type 1 diabetes; cellular immune markers for type 1 diabetes; animal models of type 1 diabetes; the pancreas in type 1 diabetes; genetics of type 1 diabetes; the role of toll-like receptors and innate immunity in type 1 diabetes; cell-based therapies for type 1 diabetes; environmental and mechanistic causes of type 1 diabetes; mechanisms of beta-cell death; role of the immune response in type 1 diabetes; and islet transplantation.

Key Topics Covered:

Preface: C.B. Sanjeevi.

Part I: Special Reports:.

- The Environmental Determinants of Diabetes in the Young (TEDDY) Study: The TEDDY Study Group and Marian Rewers.

- Type 1 Diabetes TrialNet - An International Collaborative Clinical Trials Network: Jay S. Skyler, Carla J. Greenbaum, John M. Lachin, Ellen Leschek, Lisa Rafkin-Mervis, Peter Savage, Lisa Spain, and the Type 1 Diabetes TrialNet Study Group.

- What will it Take to get Therapies Approved for Type 1 Diabetes?: Alexander Flemming.

Part II: The Pancreas in Type 1 Diabetes:.

- Islet Glia, Neurons and B-cells: The Neuroimmune-Interface in Type 1 Diabetes Pathogenesis: Hubert Tsui, Shawn Winer, Yin Chan, Dorothy Truong, Lan Tang, Jason Yantha, Geoffrey Paltser, and Hans-Michael Dosch.

- Hedgehog signalling during expansion of human Pancreatic Islet-Derived precursors: Rita Gallo, Fabio Arturo Grieco, Lorella Marselli, Elisabetta Ferretti, Alberto Gulino, Piero Marchetti and Francesco Dotta.

Part III: Update on Animal Models of Type 1 Diabetes:.

- Humanized Mice for the Study of Type 1 Diabetes and Beta Cell Function: Marie King, Todd Pearson, Aldo A. Rossini, Leonard D. Shultz, and Dale L. Greiner.

- Developing a Novel Model System to Target Insulin Reactive CD8 T Cells: Gwen S. Scott, Sigal Fishman, Alon Margalit, L. Khai Siew, Stephen Chapman, Li Wen, Gideon Gross, and F. Susan Wong.

- GATA-2 Gene (Chr6?38.5cM) Locates Close to Idd20 (Chr6?37.7cM): Lowered Expressions of the NF-?B Family Members in Dendritic Cells from NOD Mice are Associated with a Reduced Expression of GATA-2: Kazuma Takahashi, Jo Satoh, and Yoshitomo Oka.

- Measurement of CD8+ T-Cell Responses in Human Type 1 Diabetes: Emanuela Martinuzzi, Francois A. Lemonnier, Christian Boitard, and Roberto Mallone.

- Comparative Analysis of the Islet Proteome Between NOD/Lt and ALR/Lt Mice: Ping Yang, Manyu Li, Dehuang Guo, Feili Gong, Bao-Ling Adam, Mark A. Atkinson and Cong-Yi Wang.

 Continued...